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Guide

Python Virtual Environments and Dependency Management: venv, pip, uv and Poetry

PC By Pablo Cirre

Frequently Asked Questions

No — the <code>.venv</code> folder must always be in <code>.gitignore</code>. It contains absolute paths and platform-specific binaries that break on other machines. Commit only <code>requirements.txt</code> (or <code>pyproject.toml</code> + lockfile). Anyone cloning the repo runs <code>python -m venv .venv && pip install -r requirements.txt</code> to recreate it.

Use <code>uv</code> (Astral, Rust-based) when speed matters: it resolves and installs dependencies 10–100× faster than pip. For greenfield projects in 2026 it is the default. Stick with pip + venv only when your CI/CD pipeline or deployment target lacks <code>uv</code>. Migration is trivial: <code>uv pip install -r requirements.txt</code> works as a drop-in.

<code>requirements.txt</code> is a flat list of pinned packages — quick but lacks metadata. <code>pyproject.toml</code> (PEP 621) is the modern standard: it carries package name, version, build backend, dev/optional dependencies and tool config (ruff, mypy, pytest) all in one file. New projects should use <code>pyproject.toml</code>; lockfile (<code>uv.lock</code> or <code>poetry.lock</code>) replaces <code>requirements.txt</code>.

With pip: <code>pip freeze > requirements.lock</code> after install. With Poetry/uv: the lockfile is generated automatically and pins transitive dependencies + hashes. Production deploys must always use the lockfile (<code>uv pip sync uv.lock</code>) — never re-resolve from <code>requirements.txt</code> or <code>pyproject.toml</code> in production, that breaks reproducibility.

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